{"id":7016,"date":"2017-02-07T16:16:30","date_gmt":"2017-02-07T13:16:30","guid":{"rendered":"http:\/\/3alamaltanmya.com\/?p=7016"},"modified":"2017-02-07T16:16:30","modified_gmt":"2017-02-07T13:16:30","slug":"adel-m-talaat-b-v-sc-m-v-sc-ph-d-aea-scholars","status":"publish","type":"post","link":"https:\/\/3alamaltanmya.com\/?p=7016","title":{"rendered":"(Adel M. Talaat, B.V.Sc., M.V.Sc., Ph.D. (AEA-Scholars"},"content":{"rendered":"<p style=\"direction: ltr; text-align: center;\"><strong>(Adel M. Talaat, B.V.Sc., M.V.Sc., Ph.D. (AEA-Scholars<\/strong><\/p>\n<p style=\"direction: ltr; text-align: center;\">Association of Egyptian-American Scholars<\/p>\n<p style=\"direction: ltr;\"><strong><u>Abstract:<\/u><\/strong><\/p>\n<p style=\"direction: ltr;\">Tuberculosis (TB) in humans and bovine tuberculosis (BTB) in animals are classic examples of chronic infections characterized by the formation of granulomatous lesions in organs, mainly lungs and lymph nodes. TB and BTB are caused by slowly growing bacilli, mainly, Mycobacterium tuberculosis and M. bovis, respectively. In the developing countries, BTB represent a major problem with a prevalence that could reach up to 10-15% of cattle herds in some parts of Africa. In Egypt, BTB transmission among animals and from animals to humans represents a major problem because of the complexity of animal husbandry and animal trade. In this project, our teams in both USA and Egypt used whole genome sequence analysis (WGSA) to examine the dynamics of BTB transmission among 5 different regions within the Nile Delta of Egypt. During the years of 2012-2015, several farms were visited and M. bovis isolates from the same herds were analyzed. We also collected more than 50 isolates of M. tuberculosis from human cases for WGSA. As expected, farms with a known history of risky management behavior were associated with high level of BTB prevalence that reached up to 45% in some herds. Interestingly, WGASA was able to trace dynamics of BTB transmissions among herds when source and timing of infection were verified with available historical data. Moreover, isolates belong to M. bovis BCG lineage or those with drug resistance phenotypes were identified. Interestingly, all M. tuberculosis isolates were very homogenous and belonged to lineage III, unlike other neighboring countries in the Middle East. In this presentation, we will discuss the key outcomes of this project highlighting the importance of ecological combined with genomic analyses of TB and BTB.<\/p>\n<p style=\"direction: ltr;\">This article was published in <a href=\"http:\/\/3alamaltanmya.com\/\">3alamaltanmya<\/a><\/p>\n<p style=\"direction: ltr;\">sponsored by <a href=\"http:\/\/www.mahafouad.net\/%D8%B9%D9%86-%D8%A7%D9%84%D8%A7%D9%83%D8%A7%D8%AF%D9%8A%D9%85%D9%8A%D9%87\">Future Builders International Academy<\/a><\/p>\n<p style=\"direction: ltr;\">Led by <a href=\"http:\/\/www.mahafouad.net\/%d8%b9%d9%86-%d8%af-%d9%85%d9%87%d8%a7-%d9%81%d8%a4%d8%a7%d8%af\/\">Dr.Maha Fouad<\/a><\/p>\n<p><img decoding=\"async\" class=\"tie-appear alignleft\" style=\"direction: ltr;\" src=\"http:\/\/3alamaltanmya.com\/wp-content\/uploads\/e5f2ef68-75e1-4678-9ffc-3479da505483-300x177.jpg\" alt=\"e5f2ef68-75e1-4678-9ffc-3479da505483\" \/><\/p>\n<p style=\"direction: ltr;\">[<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Adel M. Talaat, B.V.Sc., M.V.Sc., Ph.D. (AEA-Scholars Association of Egyptian-American Scholars Abstract: Tuberculosis (TB) in humans and bovine tuberculosis (BTB) in animals are classic examples of chronic infections characterized by the formation of granulomatous lesions in organs, mainly lungs and lymph nodes. TB and BTB are caused by slowly growing bacilli, mainly, Mycobacterium tuberculosis and &hellip;<\/p>\n","protected":false},"author":1,"featured_media":7022,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11953],"tags":[14523,14746,14527,14529,14747],"class_list":["post-7016","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-11953","tag-3alamaltanmya","tag-bovine-tuberculosis","tag-fbia","tag-future-builders-international-academy","tag-tuberculosis"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>(Adel M. 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Talaat, B.V.Sc., M.V.Sc., Ph.D. (AEA-Scholars Association of Egyptian-American Scholars Abstract: Tuberculosis (TB) in humans and bovine tuberculosis (BTB) in animals are classic examples of chronic infections characterized by the formation of granulomatous lesions in organs, mainly lungs and lymph nodes. 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